{"product_id":"global-insulinoma-treatment-market-2023-2030","title":"Global Insulinoma Treatment Market - 2023-2030","description":"\u003cp\u003eGlobal Insulinoma Treatment Market - 2023-2030\u003cbr\u003e\nGlobal Insulinoma Treatment Market reached US$ YY million in 2022 and is expected to reach US$ YY  million by 2030 growing at a CAGR of YY% during the forecast period 2023-2030.\u003c\/p\u003e\n\n\u003cp\u003eInsulinomas are rare pancreatic endocrine tumors that can be benign or malignant. Only 10% of insulinomas are malignant. The main symptom is hypoglycemia, i.e., a decrease in blood sugar levels due to the oversecretion of insulin. Most insulinomas are non-cancerous. Hence, the drugs used are to decrease the amount of insulin secreted by islet cells in the pancreas.\u003c\/p\u003e\n\n\u003cp\u003eSurgery is the primary treatment for insulinomas. However, somatostatin analogs such as octreotide and lanreotide are given to lower insulin levels. Nearly 5-12% of all insulinomas account for metastatic insulinomas. Once the metastasis spreads to lymph nodes or the liver, the survival span is about two years.\u003c\/p\u003e\n\n\u003cp\u003eMarket Dynamics: Drivers \u0026amp; Restraints\u003c\/p\u003e\n\n\u003cp\u003eIncreasing incidence of neuroendocrine tumors\u003c\/p\u003e\n\n\u003cp\u003eInsulinomas are neuroendocrine tumors leading to insulin hypersecretion and hypoglycemia. Incidence of NET has increased across the globe in past decades, predominantly gastrointestinal, pancreatic, and bronchial sites. These tumors are caused by various environmental factors which lead to gene mutations. The prevalence of insulinoma, a prominent type of neuroendocrine tumor, has been increasing in the past two years.\u003c\/p\u003e\n\n\u003cp\u003eThe incidence of insulinoma is 1 to 4  per million per year. Insulinoma is a single benign tumor; in 5.8% of cases, it can be malignant. Over 87.5% of patients get cured (being free of symptoms for at least six months) after surgery. The majority of insulinoma are between 30-60 years of age, around 59% account for women.\u003c\/p\u003e\n\n\u003cp\u003eIn March 2022, according to the American Society of Clinical Oncology, more than 12,000 people in the United States are diagnosed with neuroendocrine tumors annually. Approximately 171,000 people are living after the diagnosis of NET.\u003c\/p\u003e\n\n\u003cp\u003eAccording to Cancer Australia.gov, in 2022, the estimated number of new neuroendocrine tumors diagnosed is 5437, of which 2846 are males and the rest are females. Compared to 2018, the number of people diagnosed with NET kept increasing.\u003c\/p\u003e\n\n\u003cp\u003eFurthermore, advancements in drug discoveries, increasing product launches, and rising awareness about diabetes, and hypoglycemia are a few factors which are expected to drive the market in the forthcoming period.\u003c\/p\u003e\n\n\u003cp\u003eAdverse effects of somatostatin analogs\u003c\/p\u003e\n\n\u003cp\u003eSomatostatin analogs are designed for anti-tumor activity and cause many adverse effects, such as steatorrhea, which can be controlled with medication. It causes occasional nausea, gastrointestinal cramps, and malabsorption. It mainly inhibits gall bladder contractions, which leads to gallstones. In 2023, according to the National Center for Biotechnology Information, nearly 27% of patients treated with Sandostatin developed gallstones.\u003c\/p\u003e\n\n\u003cp\u003eSegment Analysis\u003c\/p\u003e\n\n\u003cp\u003eThe global insulinoma treatment market is segmented based on disease type, treatment type, end user, and region.\u003c\/p\u003e\n\n\u003cp\u003eThe  Somatostatin analogs segment accounted for approximately 46.2% of the market share\u003c\/p\u003e\n\n\u003cp\u003eSomatostatin analogs are used as a first-line treatment for neuroendocrine tumors. As these have anti-proliferative properties, these analogs are extensively used to treat neuroendocrine tumors. They are more potent when compared to other drugs as they block the activity of the tumor near the pancreas that is removed later by surgery. Currently, only two analogs are available for the treatment, and the others are still in the pipeline.\u003c\/p\u003e\n\n\u003cp\u003eIn September 2023, Novartis declared a Phase III NETTER-2 trial with Lutathera. First-line treatment with Lutathera and long-acting octreotide significantly improved in patients with newly diagnosed somatostatin receptors.\u003c\/p\u003e\n\n\u003cp\u003eIn October 2022,  ITM Isotope Technologies Munich SE, a biotechnology company, received Fastrack designation from the US Food and Drug Administration for  ITM-11 (edotreotide) for treating neuroendocrine tumors.\u003c\/p\u003e\n\n\u003cp\u003eGeographical Analysis\u003c\/p\u003e\n\n\u003cp\u003eNorth America accounted for approximately 41.3% of the market share in 2022\u003c\/p\u003e\n\n\u003cp\u003eNorth America is expected to hold the largest market share due to the high rates of type 1 and type 2 diabetic individuals in the U.S. According to the diabetes journal organization, hypoglycemic individuals in the U.S. jumped 25% to 32% by 2019. Neuroendocrine tumors affect about 5 in 100,000 people. More than 12,000 new cases are diagnosed yearly, and as many as 125,000 people with these tumors live in the U.S.\u003c\/p\u003e\n\n\u003cp\u003eApproximately 12,000 - 15,000 Canadians with NETs, only 10% get accurate diagnosis and treatment.  Nearly 552 Canadians with either type 1 or type 2 diabetes, almost two-thirds of total respondents reported experiencing at least one hypoglycemic event, such as insulinomas.\u003c\/p\u003e\n\n\u003cp\u003eCOVID-19 Impact Analysis\u003c\/p\u003e\n\n\u003cp\u003eCOVID-19 has had a very slight impact on the insulinoma treatment market. There is a halt in the supply chain of drugs due to the implementation of lockdowns worldwide. A shift in the focus of clinical trials was observed for developing vaccines and medicines. There is a decreased research and development in the oncology sector during COVID 19. Due to the fear of visiting the hospitals, the diagnosis and treatment were postponed and done later.\u003c\/p\u003e\n\n\u003cp\u003eCompetitive Landscape\u003c\/p\u003e\n\n\u003cp\u003eThe major global players in the insulinoma treatment market include Baxter International Inc, Salvavidas, AdvaCare Pharma, Merck KGaA, Accord Healthcare US, Midas Pharma GmbH, Biosynth, Livealth, Ipsen Biopharmaceuticals, Inc., Cipla USA, Inc. among others.\u003c\/p\u003e\n\n\u003cp\u003eKey Developments\u003cbr\u003e\n• In August 2023, Exelixis, Inc. declared positive results from the phase 3 cabinet pivotal trial evaluating Cabozantinib in Advanced Pancreatic and Extra Pancreatic Neuroendocrine Tumors (pNET).\u003cbr\u003e\n• In November 2022, Tetris Pharma, a subsidiary of Arecor Therapeutics, launched a prefilled auto-injector pen for hypoglycemia that is caused due to insulinoma in Germany which has been approved for the treatment of severe hypoglycemia in children and adults.\u003c\/p\u003e\n\n\u003cp\u003eWhy Purchase the Report?\u003cbr\u003e\n• To visualize the global insulinoma treatment market segmentation based on disease type, treatment type, end user and region as well as understand key commercial assets and players.\u003cbr\u003e\n• Identify commercial opportunities by analyzing trends and co-development.\u003cbr\u003e\n• Excel data sheet with numerous data points of insulinoma treatment market-level with all segments.\u003cbr\u003e\n• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.\u003cbr\u003e\n• Product mapping available as excel consisting of key products of all the major players.\u003c\/p\u003e\n\n\u003cp\u003eThe global insulinoma treatment market report would provide approximately 61 tables, 57 figures, and 195 Pages.\u003c\/p\u003e\n\n\u003cp\u003eTarget Audience 2023\u003cbr\u003e\n• Manufacturers\/ Buyers\u003cbr\u003e\n• Industry Investors\/Investment Bankers\u003cbr\u003e\n• Research Professionals\u003cbr\u003e\n• Emerging Companies\u003c\/p\u003e","brand":"Life Science","offers":[{"title":"October, 2023 \/ 195 Pages \/ MCW16256136","offer_id":47650520269106,"sku":null,"price":5220.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.hardmanwell.com\/products\/global-insulinoma-treatment-market-2023-2030","provider":"HARDMAN AND WELL MANAGEMENT CONSULTANCIES L.L.C","version":"1.0","type":"link"}